LUMINATE will bring regenerative medicine directly in the patient to heal the knee bone and cartilage atfer traumatic injuries. Our solution will synergize innovations in novel bioprinting technologies and biomaterials to introduce a more effective and efficient one-stage regenerative procedure
A traumatic injury to the knee can mean more than just immediate pain, as it can lead to long-term discomfort, limited movement, and a higher chance of developing arthritis. Unfortunately, current treatments are often expensive, hard to access, and may only postpone the need for a knee prosthesis.
Developing a new bioprinting technology to print directly inside the patient body
Creating novel biomaterials tailored for the bone and cartilage and bone tissues, and mixing them with patient-derived cells for a personalized treatment
Exploiting Artificial Intelligence and advanced computational models to support the project technical development and provide surgeons with improved tools
Accelerate the pathway to clinical translation, by taking into consideration regulatory aspects throughout the whole project development
By leveraging cutting-edge 3D bioprinting technology, LUMINATE introduces EndoFLight, a minimally invasive solution designed to regenerate cartilage and bone tissue directly at the site of injury. This breakthrough aims to prevent post-traumatic osteoarthritis (PTOA) and reduce the need for invasive joint replacements.
Backed by a consortium of leading universities, medical centers, and industry experts across Europe, LUMINATE aligns with Horizon Europe’s mission to advance healthcare, sustainability, and biomedical technology
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Lead teacher and 1-2 year olds
Teacher: 2-3 year olds
Teacher: 3-4 year olds
The LUMINATE project embarks on a journey to redefine osteochondral (OC) tissue regeneration, ensuring that patients suffering from knee cartilage and bone injuries receive groundbreaking, personalized treatment. Through its innovative in situ bioprinting technology, LUMINATE develops a minimally invasive, one-stage solution that could eliminate the need for traditional joint replacement surgeries. Each work package (WP) plays a crucial role in shaping this future, combining cutting-edge bioprinting, biomaterial engineering, artificial intelligence, and clinical validation to bring EndoFLight—the project’s revolutionary bioprinting suite—into reality.