Pioneering regenerative medicine to restore knee joint function after traumatic injuries
LUMINATE is an EU-funded initiative dedicated to regenerating soft tissue and bone structures damaged by trauma. Using cutting-edge filament light bioprinting and innovative biomaterials, the project develops therapeutic solutions that integrate seamlessly into the body, restoring both cartilage and bone. Its ultimate goal is to reduce pain, improve joint function, and delay the need for invasive procedures like knee replacement surgery.
The LUMINATE project focuses on four pillars, combining technology, science, and clinical expertise to create new regenerative solutions that can improve the lives of patients with knee injuries.
Develop new bioprinting technology to print directly inside the patient body.
Create novel biomaterials tailored for the bone and cartilage and bone tissues and mixing them with patient-derived cells for a personalized treatment.
Exploite AI and advanced computational models to support the project technical development and provide surgeons with improved tools.
Accelerate the pathway to clinical translation, by taking into consideration regulatory aspects throughout the whole project development.
Combining biomaterials engineering, 3D bioprinting, and regenerative medicine, LUMINATE pioneering the synergy of technologies that enable precise in situ regeneration of cartilage and subchondral bone. Through filament light bioprinting, micro-extrusion, and AI-supported design, the project creates innovative therapeutic solutions to treat osteochondral defects effectively and safely.
A traumatic injury to the knee can mean more than just immediate pain, as it can lead to long-term discomfort, limited movement, and a higher chance of developing arthritis. Unfortunately, current treatments are often expensive, hard to access, and may only postpone the need for a knee prosthesis.
The LUMINATE project aims to have a significant clinical impact by developing innovative regenerative therapies that restore both cartilage and subchondral bone tissue after traumatic injuries. By enabling effective in situ regeneration, these treatments can improve joint function, reduce pain, and prevent or delay the onset of osteoarthritis. Ultimately, LUMINATE seeks to offer patients safer, less invasive alternatives to traditional surgical procedures such as joint replacements, improving their quality of life and long-term mobility.
Stay informed about LUMINATE’s latest milestones, publications, and events across Europe.
Follow our progress as we advance regenerative medicine and bioprinting technologies.
The use of artificial intelligence in medicine requires software user interfaces that ensure usability, transparency, and compliance with the European
From September 14 to 17, 2025, the LUMINATE project was proudly featured at the International Conference on Biofabrication, held in
The LUMINATE project will be proudly presented at the 34th Annual Conference of the European Society for Biomaterials (ESB), taking
