Luminate

Lighting the way towards in situ osteochondral regeneration through microextrusion and filamented light bioprinting

LUMINATE will bring regenerative medicine directly in the patient to heal the knee bone and cartilage atfer traumatic injuries. Our solution will synergize innovations in novel bioprinting technologies and biomaterials to introduce a more effective and efficient one-stage regenerative procedure

A traumatic injury to the knee can mean more than just immediate pain, as it can lead to long-term discomfort, limited movement, and a higher chance of developing arthritis. Unfortunately, current treatments are often expensive, hard to access, and may only postpone the need for a knee prosthesis.

The LUMINATE solution is based on four main pillars

New bioprinting technology

Developing a new bioprinting technology to print directly inside the patient body

Creating novel biomaterials

Creating novel biomaterials tailored for the bone and cartilage and bone tissues, and mixing them with patient-derived cells for a personalized treatment

Exploiting AI

Exploiting Artificial Intelligence and advanced computational models to support the project technical development and provide surgeons with improved tools

Accelerating Clinical Translation

Accelerate the pathway to clinical translation, by taking into consideration regulatory aspects throughout the whole project development

About the project

LUMINATE is an innovative research initiative under Horizon Europe, dedicated to transforming the treatment of osteochondral (OC) injuries

By leveraging cutting-edge 3D bioprinting technology, LUMINATE introduces EndoFLight, a minimally invasive solution designed to regenerate cartilage and bone tissue directly at the site of injury. This breakthrough aims to prevent post-traumatic osteoarthritis (PTOA) and reduce the need for invasive joint replacements.

Backed by a consortium of leading universities, medical centers, and industry experts across Europe, LUMINATE aligns with Horizon Europe’s mission to advance healthcare, sustainability, and biomedical technology

15

PARTNERS

9

COUNTRIES

4

YEARS

1 January 2025 1 January 2029

7,5M €

BUDGET

Daily activities

Designed to help children realize their potential

Morning Huddles

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The Basics

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Play Stations

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Learning Lab

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Superfoods

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Outdoor Play

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Meet the teachers

Experts in giving your children best start

Ella Stark

Lead teacher and 1-2 year olds

Harriet Bailey

Teacher: 2-3 year olds

Melinda Schiller

Teacher: 3-4 year olds

What parent say
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Ramona Altenwerth

More than just a joyful place

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